Modules
- Year 1
- Year 2
- Introduction to Year 2 and Year Outcomes
- Cardiorespiratory 2
- Metabolism 2
- Brain and Behaviour 2
- Human Development 2
- Human Sciences and Public Health 2
- Locomotor 2
- Cancer Week
- Moving and Handling Training
- Year 2 Lifesaver Programme
- Clinical Communication Skills
- Medicine in Society 2
- Extended Patient Contact
- Student Selected Component (SSC)
- Year 3
- Introduction to Year 3 and Year Outcomes
- Clinical Science and Professionalism (Weeks 1-3)
- Cardiovascular, Respiratory and Haematology (CR3)
- Gastroenterology and Cancer (MET3A)
- Public Health
- Endocrinology and Renal Medicine (MET3B)
- General Practice and Community Care
- Student Selected Component (SSC)
- Clinical and Communication Skills
- Year 4
- Introduction and Year 4 Outcomes
- Obstetrics and Gynaecology
- Child Health
- HIV & Sexual Health
- Musculoskeletal
- Health Care of the Elderly
- Neuroscience
- Dermatology
- General Practice and Community Care
- Psychiatry
- Ear, Nose and Throat
- Global Health and Ethics
- Ophthalmology
- Clinical & Communication Skills
- Student Selected Component (SSC)
- Year 5
- Introduction to Year 5 and Year Outcomes
- Teaching Week 1
- Teaching Week 2
- Anaesthesia & ITU (AN & ITU)
- Breaking Bad News
- Clinical Pharmacology & Therapeutics
- Community Care
- Doctors as Teachers and Educators (DATE)
- Emergency Medicine (EMERG MED)
- General (Internal) Medicine (G(I)M)
- Immediate Life Support (ILS)
- Student Assistantship
- Simulation
- Surgery
- Student Selected Component (SSC)
- Year GEP 1
Year GEP 1 GEP/CO2: Carriage of Oxygen
- Dr Rachel Ashworth
- r.ashworth@qmul.ac.uk
Teaching Material for this Module
Introduction
This module introduces you to the anatomy and physiology of the cardiorespiratory system, how it works in normal subjects, and some of the major pathological conditions that can occur. As you probably already know, respiratory diseases (e.g. asthma, tuberculosis, lung cancer) and cardiovascular disease (atherosclerosis, strokes, myocardial infarction) are major causes of disability and death in the UK.
Learning delivery is through a mix of lectures, practicals, microanatomy sessions, problem-based learning (PBLs) and self-directed learning.
Index
- General Outcomes for the Cardiovascular System
- General Outcomes for the Respiratory System
- General Outcomes for Renal and Urinary System
- General Outcomes for Haematology
- Asthma (Priority 1*)
- General Outcomes for the Cardiovascular System
- Medical knowledge: ANATOMY (TD 8.1)
- Circulation of the Shoulder, Arm and Hand
- Lymphatic System
- Circulation of the lower limb and foot
- Medical knowledge: PHYSIOLOGY (TD 8.2)
- Smooth and Cardiac Muscle
-
Blood Pressure
- Describe the renin-angiotensin-aldosterone system and explain its role in blood pressure regulation
- Describe the physiological sensors and effectors for neuronal control of arterial blood pressure
- List common drugs which can be used to control hypertension and explain their mechanism of action
- Describe the position and innervation of the aortic and carotid sinus baroreceptors, their central connections, and the role of the brainstem in the control of blood pressure
- Describe the role of the vagus nerve and the sympathetic nervous system in the control of blood pressure
- The Conducting System of the Heart and the ECG
-
Haemodynamics
- Explain the relationships between cardiac output, peripheral resistance and blood pressure
- Explain the concept of arterial compliance, and describe the relationship between pulse pressure, stroke volume and compliance
- Be able to comment on the importance of Laplace's Law relating vessel radius and pressure, and how this relates to aneurysm formation.
- General Cardiovascular Physiology
- Medical knowledge: BIOCHEMISTRY (inc. Metabolism) (TD 8.3)
- Medical knowledge: ANATOMY (TD 8.1)
- General Outcomes for the Respiratory System
- Medical knowledge: ANATOMY (TD 8.1)
- Pleural Cavity and Lungs
- Medical knowledge: PHYSIOLOGY (TD 8.2)
-
General Outcomes for Respiratory Physiology
- List the functions of the respiratory system.
- Name the main structural features of the lungs
- Distinguish between respiratory and non-respiratory components of the lungs and show how histological features are related to function.
- Describe the branching pattern of the respiratory tree, commenting on the significance of the cross-sectional area at different levels
- Lung Mechanics
- The Lungs and Pulmonary Circulation
-
General Outcomes for Respiratory Physiology
- Medical knowledge: PHARMACOLOGY (TD 8.10)
- General Outcomes for Respiratory Pharmacology
- Medical knowledge: EPIDEMIOLOGY
- Medical knowledge: ANATOMY (TD 8.1)
- General Outcomes for Renal and Urinary System
- Medical knowledge: ANATOMY (TD 8.1)
-
Renal System and Urinary Tract
- Outline the general organisation of the urinary system including the kidney, ureter, bladder and urethra
- Identify the parts of the nephron and describe the role of each component in the physiologic processes involved in urine production
- Describe the vasculature of the kidney, relating its unique features to the physiology of urine production and nourishment of the nephron
-
Renal System and Urinary Tract
- Medical knowledge: PHYSIOLOGY (TD 8.2)
-
Renal Function
- Identify the parts of the nephron and describe the role of each component in the physiologic processes involved in urine production
- Describe the vasculature of the kidney, relating its unique features to the physiology of urine production and nourishment of the nephron
- Explain how the thick-walled, ascending limb of the loop of Henle plays a key role (in conjunction with ADH) in the production of either a dilute or concentrated urine to meet the requirements of water balance.
- Identify the components of the juxtaglomerular apparatus and describe its role in regulation of blood and urine volumes and renal homeostasis.
- Homeostasis
-
Renal Function
- Medical knowledge: PATHOLOGY (TD 8.7)
- Medical knowledge: ANATOMY (TD 8.1)
- General Outcomes for Haematology
- Medical knowledge: PHYSIOLOGY (TD 8.2)
-
Structure and Function of Blood
- List the cellular components of blood cells and outline their roles in the carriage of oxygen and carbon dioxide, immunity / allergy and haemostasis
- List the major chemical components of plasma, and comment on the role of these in clotting, immunity, colloid pressure and buffering
- Outline the production of blood cells from pluripotent haemopoietic stem cells and the regulation of erythropoiesis and myelopoiesis
- Outline the response to anaemia
- Define the parameters of a full blood count and give an outline classification of anaemia
-
Haemostasis and Thrombosis
- Describe the nature and function of platelets; explain what is meant by thrombocytopenia
- Describe the normal coagulation pathway and how it is activated by: tissue damage, contact of blood with tissue collagen or glass.
- Describe the roles of Vitamin K, platelets, calcium, serine proteases and modifier proteins in the clotting process
-
Structure and Function of Blood
- Medical knowledge: PHARMACOLOGY (TD 8.10)
- Medical knowledge: PHYSIOLOGY (TD 8.2)
- Asthma (Priority 1*)