Modules
- Year 1
- Year 2
- Introduction to Year 2 and Year Outcomes
- Cardiorespiratory 2
- Metabolism 2
- Brain and Behaviour 2
- Human Development 2
- Human Sciences and Public Health 2
- Locomotor 2
- Cancer Week
- Moving and Handling Training
- Year 2 Lifesaver Programme
- Clinical Communication Skills
- Medicine in Society 2
- Extended Patient Contact
- Student Selected Component (SSC)
- Year 3
- Introduction to Year 3 and Year Outcomes
- Clinical Science and Professionalism (Weeks 1-3)
- Cardiovascular, Respiratory and Haematology (CR3)
- Gastroenterology and Cancer (MET3A)
- Public Health
- Endocrinology and Renal Medicine (MET3B)
- General Practice and Community Care
- Student Selected Component (SSC)
- Clinical and Communication Skills
- Year 4
- Introduction and Year 4 Outcomes
- Obstetrics and Gynaecology
- Child Health
- HIV & Sexual Health
- Musculoskeletal
- Health Care of the Elderly
- Neuroscience
- Dermatology
- General Practice and Community Care
- Psychiatry
- Ear, Nose and Throat
- Global Health and Ethics
- Ophthalmology
- Clinical & Communication Skills
- Student Selected Component (SSC)
- Year 5
- Introduction to Year 5 and Year Outcomes
- Teaching Week 1
- Teaching Week 2
- Anaesthesia & ITU (AN & ITU)
- Breaking Bad News
- Clinical Pharmacology & Therapeutics
- Community Care
- Doctors as Teachers and Educators (DATE)
- Emergency Medicine (EMERG MED)
- General (Internal) Medicine (G(I)M)
- Immediate Life Support (ILS)
- Student Assistantship
- Simulation
- Surgery
- Student Selected Component (SSC)
- Year GEP 1
Year GEP 1 GEP/M&P: Movement and Posture
- Dr Lesley Robson
- l.g.robson@qmul.ac.uk
Teaching Material for this Module
Introduction
Disorders of the locomotor system are extremely common in the community. They account for up to 30% of General Practitioner consultations and result in huge costs to the economy in terms of time lost from work, costs to industry and the individual as well as significant disability. Some locomotor diseases may also reduce life span significantly. This module is designed to introduce you to the normal structure and function of the locomotor system.
Learning delivery will be via lectures, practicals, computer assisted learning (CAL), clinical demonstrations, PBL and self-directed learning.
Sessions
- Lecture: Introduction to Movement and Posture
- Lecture: Introduction to Skin
- Lecture: Joint Structure and Function
Teaching Material for this Session
- To explain the 3 major categories of joints
- To understand and explain how the synovial fluid and articular cartilage contribute to synovial joint function
- Be able to identify the three main types of joints and how, structurally, they influence the amount of movement possible
- To understand the basics of how joints are affected by disease
- Understand how the articular cartilage and synovial fluid contribute to the function of synovial joints
- Lecture: Introduction to Imaging
Teaching Material for this Session
- Describe the uses of, and the differences between, the following medical imaging techniques: plain (X-Ray) films; computerised tomography (CT); magnetic resonance imaging (MRI) and ultrasound
- Discuss why knowledge of anatomy is vital to appreciate the applications of imaging to medicine.
- Discuss the use of contrast: Barium, iodine, gadolinium
- Lecture: Articular Cartilage and Synovium
Teaching Material for this Session
- To describe the normal microanatomy of the articular cartilage and how this changes with normal ageing and in disease states
- Understand the main biochemical components of synovial fluid
- Understand how glycosaminoglycans contribute to lubricating properties of the synovial fluid
- Understand how synovial fluid is produced
- To be aware of the changes in disease states
- Lecture: Peripheral Vasculature
- Lecture: Bone Metabolism and Growth
- Lecture: Muscle - Structure and Function
- Lecture: The Neuromuscular Junction
- Lecture: Deratomes, Peripheral Nerves & Plexi
- Lecture: Pelvis and Hip
- Lecture: Action & Membrane Potentials
- Describe the structure of a typical cell membrane
- Explain the origin of osmotic forces acting in the cell
- Explain the different ways in which plant and animal cells cope with osmotic forces
- Explain why there is an imbalance in potassium concentration inside and outside animal cells
- Explain the necessity for a sodium pump
- Describe the special features of voltage gated sodium channels
- Draw a diagram of the ionic currents occurring during an action potential
- Lecture: Muscles of Hip and Neurovascular Supply to Thigh
Teaching Material for this Session
- Understand the movements possible at the hip joint and the muscles that produce these movements.
- To review the major arteries in the lower limb
- Identify the positions where arterial pulsations may be felt in the lower limb
- Understand the mechanisms of how blood returns from the veins of the lower limb to the heart
- Describe the formation of the lumbar and sacral plexi
- Describe the course of the nerves in the lower limb
- Understand the functional problems arising from damage to these nerves
- Lecture: Muscle in Health and Disease
- Lecture: Clinical Conditions of Hip
- Lecture: Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
- Dissection 1 - Gluteal Region
- Lecture: Femoral Triangle
- Dissection 2- Fermoral Triangle
- Lecture: Paediatric Condtions of the Hip
- Lecture: Metabolic Conditions of Bone
- Lecture: Popliteal Fossa
- Lecture: Clinical Conditions of the Knee
- Lecture: Surface Anatomy of Knee
- Lecture: Ankle and Foot
- Dissection 3 - Popliteal Fossa and Knee
- Lecture: Overview of the Lower Limb & Lymphatics
Teaching Material for this Session
- Review the anatomy and function of the lower limb
- Describe the lymphatic drainage of the lower limb
- Describe the location of the lymph nodes that drain the lower limb
- Describe briefly how the lymph drains in the rest of the body
- Describe the clinical problems that can arise from problems of the lymphatic drainage
- Lecture: The Knee
- Lecture: Gait Walking and Posture
Teaching Material for this Session
- List the functions of the lower limb and the anatomical specializations stabilize that the lower limb
- Describe the changes from a double support to a single support
- Describe the events in the normal walking cycle
- Describe the action of the main muscles involved
- Analyse some types and causes of abnormal gait
- Dissection 4 - Lower Leg and Dorsum of Foot
- Dissection 5 - Calf and muscle
- Lecture: Bone Fractures and Fracture Healing
- Lecture: Degenerative Bone and Joint Conditions
- Lecture: Basic Immunolgy and Joint Diseases
- Lecture: Joint and Bone Infections
- Lecture: Pectoral Girdle Shoulder and Arm
- Lecture: Rheumatoid Arthritis
- Lecture: Brachial Plexus and Axilla
- To describe the spinal nerve roots that contribute to the brachial plexus
- To describe how the brachial plexus results in the 5 terminal nerves of the upper limb
- To describe the path of these nerves through the pectoral region and axilla into the arm
- To describe the boundaries of the axilla and the structures that pass through
- Lecture: Disease Modifiying Antirheumatics
- Lecture: Elbow and Cubital Fossa
- Lecture: Clinical Problems of the Shoulder and elbow
Teaching Material for this Session
- To describe the anatomical implications of fractures to the clavicle
- To describe the anatomical implications of dislocations of the glenohumeral joint
- To describe the rotator cuff anatomy to clinical problems
- To describe the anatomical relationships of nerves and blood vessels that could be compromised by fractures to the humerus
- Lecture: Forearm and Hand
- To describe the osteology of the forearm, carpals and hand
- To describe the muscles that are located in the forearm and their actions
- To describe the contents of the carpal tunnel and its boundaries
- To describe the arrangement of the long flexor tendons at the wrist and in the hand and how this influences the movements they produce and how they are protected.
- Lecture: Crystal Arthropathies
- Lecture: Orthopaedics
- Lecture: Intervertebral Discs and Movements of the Back
- Lecture: Clinical Back Problems
- Lecture: Analgesia and Pain Management
- Lecture: Movements of the Hand and Functional Anatomy of the Upper Limb
- Define the term opposition of the hand
- Understand the movements that are possible at the various joints of the hand
- Understand the 2 main categories of grip and the main sub-divisions within each
- Understand how nerve damage can affect the function of the hand
- To understand the functional anatomy of the upper limb
- To understand the modifications for movement and the clinical relevance of these modifications
- Lecture: Treatment options for Osteoarthritis
- Histology: Bone, Muscle and Myotendinous Junctions
- Microanatomy: Epithelia
- Recognise the various epithelial cell types in photomicrographs and predict their function from their structure
- Understand and master the use of the system for classifying different types of lining epithelia based on number of layers and shape of cells.
- Recognise, name and understand the function of different components of the basement membrane.
- Recognise glandular tissue in photomicrographs, indentify the gland type and its likely function.
- Recognise the basement membrane and list its function
- Microanatomy: Locomotor
- CAL: Self Directed Learning - Spinal Cord
- GEP1 - PBL1: JENNIFER AND HER FAMILY
Teaching Material for this Session
Martha is a normal height (1m 60cm) 34 year old woman she is expecting her 1st child and is at 10 weeks gestation.As Martin her husband, who is a financial advisor for a bank, has achondroplasia, the family were referred to a clinical geneticist. Martin agreed to a genetic test and after PCR and sequencing was found to be heterozygous for the mutation c.1138G>A (p.Gly380Arg) in the FGFR3 gene.The family were offered prenatal diagnosis but, after much discussion, they declined. At 34 weeks, Martha had ultrasonography of the fetus that revealed frontal bossing with depressed nasal bridge, representing midfacial hypoplasia, contracted scull base shortened long bones while crown-rump length was within the normal range.A healthy baby girl was born and named Jennifer, by caesarian section. As Jennifer grew up she developed bow-legs (genu-varum), a marked sway (lordosis) to her lower back with a small thoracic hump (kyphosis), she also had an operation to enlarge the foramen magnum and decompress the cervical spinal cord.She had above normal intelligence and went to a regular primary school and stated that she wanted to become a doctor when she grew up.
- GEP1 - PBL2: A MUSCLE PROBLEM
Teaching Material for this Session
Sonia is a 25 year old who is referred by her GP for electromyography and nerve conduction studies (EMG and NCS) because of a 9 month history of low back pain and difficulty in walking. The symptoms have become progressively worse since their onset. There is associated pain in the right anterior thigh which Sonia says is moderate in severity and is dull in quality while the low back pain was severe and sharp in nature. The pain increased with activity. What prompted Sonia to go to her GP in the 1stinstance was that a week after the symptoms began she noticed that her legs would “give way”, especially involving the right side more than the left, but now both sides are equally affected, and have resulted in numerous falls. Sonia also now has problems going up and down stairs and of getting in and out of chairs. She has had physiotherapy sessions over the last few months but without any improvement. Her GP prescribed diclofenac for the pain. She now has an appointment with the neuromuscular laboratory for EMG and NCS assessment. On physical examination, her blood pressure is 110/70 mmHg, heart rate 80 beats per min. There is no cervical lymphadenopathy. Her cardiac, respiratory and abdominal examinations were unremarkable. There is no fever or erythema of any joint adjacent skin in all extremities. Her range of motion of neck, shoulders and all major joints of the upper and lower extremities was normal bilaterally. Coordination, pin-prick, light touch, joint position and vibration sensation in the upper and lower limb are also all normal. Motor examination revealed 4/5 strength in the upper and lower limbs, except for 2/5 bilateral hip extensor and abductor strength. The quadriceps and Achilles reflexes were absent, the biceps reflex was present. She displayed a bilateral Trendelenberg gait with an extension lurch and a wide base of support. The elctrodiagnostic results suggest presynaptic neuromuscular junction disorder and specifically Lambert-Eaton myasthenic syndrome, confirmed by tests for antibodies to P/Q calcium channels being positive while those to acetylcholine receptors were negative. Sonia was admitted to the hospital and was given a course of intravenous immunoglobulin after which she showed a marked improvement of her muscle fatigue and gait dysfunction.
- GEP1 - PBL3: THE SNAPPING HIP
- GEP1 - PBL4: PAGET'S DISEASE OF THE BONE
- GEP1 - PBL5: THE DANGERS OF SKINNY JEANS: THE FASHION VICTIM
Teaching Material for this Session
Kate is a 35 year old who is brought into the Accident and Emergency department with severe weakness of both ankles around midnight. When her history is taken she reports that she was helping her younger sister move house all day and that this meant she had been squatting for a considerable amount of time as she emptied cupboards and filled cardboard boxes. She is wearing a pair of skinny jeans that she has been wearing all day and reports that her jeans have felt increasingly tight and uncomfortable during the day. That night while she had walked home and she had noticed that she was dragging her toes and stumbled a few times. When she got home the bilateral foot drop got worse and she had fallen and her partner had to help up as she could not get up on her own. The weakness in her ankles had continued to get worse and so her partner has brought her in to the hospital.
On examination her lower legs were markedly oedematous bilaterally, with the swelling worse on the right side. She is still wearing the skinny jeans and these had to be removed by cutting them off. There was bilateral severe global weakness of the ankle and toe movements with less movement possible on the right. Muscle power at the hips and knees was normal, the knee jerk reflex was normal but the ankle jerk reflex were absent. Sensation was impaired over the lateral aspects of both lower legs and the dorsum of the foot and the sole of the foot. All peripheral pulses were normal and the feet were warm and well perfused.
Blood was taken and results showed markedly elevated creatine kinase (73,215 IU/L normal range for women 24-170 IU/L). Renal function was normal but her urine was darker in colour and contained traces of myoglobin. A CT scan was performed and showed marked oedema and hypoattenuation of the posterior calf muscles, worse on the right, consistent with myonecrosis. Nerve conduction studies showed a conduction block in both common peroneal nerves between the popliteal fossa and fibular head. Compound muscle action potential amplitudes of the tibial nerves were also diminished with stimulation in the popliteal fossa, compared with the ankle.Sural and superficial peroneal sensory action potentials were normal amplitude bilaterally, but the right medial plantar sensory action potential was absent and the reduced on the left.
She was started on intravenous isotonic saline.The oedema and neurological function of the lower limbs improved over the 4 days she was in hospital that she was discharged and was able to walk unaided.
- GEP1 - PBL6: TREVOR AND HIS BAD HIPS
Teaching Material for this Session
Trevor is a 66 year old male with a history of severe COPD with hyper-responsiveness and emphysematous bullae in both lung apices.He is following oxygen therapy at home (15 hrs per day) combined with bronchodilators, diuretics and steroids (prednisolone 10mg) on alternate days. He had been referred a year ago to the rheumatologists because of referred pain in the central lumbar region and in both hips especially when he walks, the pain is less when he is sitting or lying down. A pelvic radiograph showed spondylolysis with spondylolisthesis of L5 and osteoarthritis of the hip. Six months later the pain had increased and Trevor now needed a wheelchair as he found it hard to stand and move due to intense pain in both hips. A follow up radiograph was taken and showed destruction of both femoral heads and acetabulums.The most significant finding of the blood tests was leukocytes (9.5x10-3/mm3 (48.4% neutrophils), Hb 12mg/dL, Hct 36, platelets 355x10-3/mm3, ESR 32 mm/hr, and Antinuclear Antibodies, antiphospholipid antibodies and rheumatoid factor were negative). Trevor was referred to the orthopaedics team and underwent an uncemented bilateral total hip replacement, using the minimal posterior approach. During the operation no crystals were observed in the synovial fluid and cultures for bacteria and fungi were negative. The extracted femoral heads were sent for histological analysis and showed severe degenerative joint disease, avascular bone necrosis and chronic synovial inflammation.
Trevor recovery was uneventful and with physiotherapy there was significant improvement in muscular balance and pain free walking. Apart from walking with the aid of canes he has few restrictions.
- GEP- PBL 7: BELLA
- GEP- PBL 8: THE RUGBY TACKLE
Teaching Material for this Session
Matthew is an 18 year old university rugby player who attends the student health centre 6 days after an anterior dislocation of his right shoulder. He had dislocated his shoulder by being tackled by two players from the other team while playing at the weekend. He had been taken to the Royal London accident and emergency department to reduce the shoulder where the shoulder x-ray and examination had shown an anterior dislocation of the right glenohumeral joint with no fractures of the humerus and pectoral girdle, but Matt did reported numbness over his right deltoid and some tingling in his right hand, it was therefore decided to reduce the shoulder immediately while he was conscious but with anaesthesia by ultrasound guide brachial plexus nerve block. After the shoulder was reduced Matt still reported a significant amount of pain in the right shoulder and so he was advised to take diclofenac for the pain. At this presentation Matt reported that the pain was now gone, so that he no longer needed to take the diclofenac but that the he still experienced occasional paresthesia in his right ring and little fingers, but had full feeling over his right deltoid. At this examination of the shoulder there is minimal swelling but the range of movement of the right shoulder was significantly reduced, particularly abduction and external rotation. His supraspinatus muscle was also weak and caused Matt considerable pain when tested for strength, but both anterior and posterior parts of the deltoid were intact. A neurovascular exam reveals no significant deficits. Matt was sent for an MRI and this showed an anterior labral tear, and a supraspinatus tendon tear. Matt was referred to the orthopaedic team and underwent arthroscopic examination which found an extensive detachment of the glenoid labrum anteriorly and a 2 cm full thickness supraspinatus tear both of which the orthopaedic team repaired. Postoperatively Matt’s range of movement of the shoulder continued to improve and by 1 year after his operation Matt had a full range of movement and no pain and he had 90-95% of his supraspinatus strength and was given the all clear to take part on contact sports again.
- GEP- PBL 9: MONTY'S ELBOW
- GEP- PBL 10: THE BAD BACK
- GEP- PBL 11: MARTY & MANDY
- Lecture: Intro - Fascia, Compartments, Muscle Functions
Teaching Material for this Session
- To describe the structure and anatomical location of the superficial and deep fascia of the lower and upper limb and the structures that are related to these fascial layers
- To describe how the deep fascia leads to the formation of muscular compartments
- To explain how muscle function is enhanced by the fascia
- Surface Anatomy of the Foot & Ankle
- Surface Anatomy - Shoulder & Elbow
- Clinical Anatomy of the Upper Limb : Orthopaedics and paediatric Conditions
- Surface Anatomy - Wrist & Hand
- EMG
- Osteology Vertebrae, Imaging Vert Column, Surface Anatomy Back:
- Q & A Revision Session
- In-Course Assessment: Movement and Posture
- Spotter Examination: Movement and Posture
- Formative OSCE Examination
- Dissection 6 - Back, Shoulder and Triceps
- Dissection 7a - Pectoral Region
- Dissection 7b - Axilla and Anterior Compartment of the Arm
- Dissection 8 - Cubital Fossa, Flexors of the Arm and Carpal Tunnel
- Dissection 9 - Extensors and Hand